De-pigmentation is always a constant occurrence of Syringoma treatment and removal. De-pigmentation occurs every time the skin has healed after surgical excision. The use of customized peels is the least invasive treatment available and the degree of de-pigmentation is very low compared to the de-pigmentation caused by surgical excision.
The de-pigmentation will not last very long. Like after any other type of wound, it takes in the region of 3 to 4 months for the new skin to blend in with the rest. Normal sun exposure will accelerate the process.